Yohimbe interaction & cardiovascular caution
Yohimbe/yohimbine has been associated with rapid heart rate, blood-pressure problems, arrhythmias, heart attacks, and seizures, and it can interact with medications.
NCCIH specifically advises against use with MAO inhibitors and tricyclic antidepressants and recommends checking with a health care provider if you take any medicine.
NCCIH — Yohimbe: Usefulness and Safety